Bacteriology & Antibiotics

Biography

Biography: Abdullah Noori

Abstract

Introduction: E coli are life-threatening pathogens commonly isolated from patients with bloodstream infections and urinary tract infections. The rising rate of antibiotic resistant has increased the concern about this pathogen. This study was conducted to determine the antibiotic susceptibility profile of E coli isolated from patients hospitalized in Amiri Hospital, a tertiary hospital located in Kabul. Method: In this study a total of 150 samples of E coli were collected during a period of 6 months (1^st of January 2018 to 30^th of Jun 2018). The samples were taken from patients of both gender and any age group admitted in different wards of the hospital. After the confirmation of the samples as E coli by conventional laboratory tests, the antibiotic susceptibility profile was tested to 9 commonly used antibiotics by Kirby-Bauer disk diffusion and Minimal Inhibitory Concentration methods according to Clinical and Laboratory Standards Institute guideline. Results: in this study the resistance pattern to tested antibiotics was as follow: Tetracycline (61%), Ampicillin (55%), Cefuroxime (62%), Cefotaxime (80%), Cefixime (66%), Amikacin (40%), Ciprofloxacin (45%), Norfloxacin (56%), Cotrimoxazole (63%). Conclusion: this study confirmed the resistant strain of E coli to all tested antibiotics. Most of the tested strains were multi-drug resistant as those strains were resistant to three or more groups of antibiotics.